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CD5 (Mantle Cell Lymphoma Marker)(B-B8), CF594 conjugate, 0.1mg/mL

CD5 (Mantle Cell Lymphoma Marker)(B-B8), CF594 conjugate, 0.1mg/mL

ArtNr	B-BNC940995-500
Hersteller	Biotium
Menge	500 uL
Quantity options	100 uL 500 uL
Kategorie	Oncology Antibodies By Cell Type Hematology Leukemia Lymphoma Flow Cytometry Immunofluorescence Primary Antibodies By Organ Heart & Blood Cancer Lymphatic System Cancer
Typ	Antibody Monoclonal
Format	Liquid
Applikationen	FC, IF
Clon	B-B8
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1 Kappa
Citations	Inf Immunity (1996) 64(5): 1595-1599. (cell depletion)Br J Haematol (2013) 163: 182-193. (antibody internalization)
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	CD5 antigen (p56 62),LEU1,Ly12,LyA,Lymphocyte antigen T1/Leu-1,Lymphocyte glycoprotein T1/Leu1,T-cell surface glycoprotein CD5
Versandbedingung	Raumtemperatur
Lieferbar
Manufacturer - Type	Primary
Manufacturer - Applications	Functional studies (published), Flow, surface (expected), IF (expected)
Manufacturer - Category	Primary Antibodies Only
Manufacturer - Targets	CD5
Manufacturer - Conjugate / Tag	CF594
Manufacturer - Host	Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Shipping Temperature	Room temperature
Storage Conditions	Store at 2 to 8°C\|Protect fluorescent conjugates from light 2°C to 8°C
Molecular Weight	67 kDa
Manufacturer - Research Area	Immunology
Description	This antibody recognizes a 67 kDa transmembrane protein which is identified as CD5. The CD5 antigen is found on 95% of thymocytes and 72% of peripheral blood lymphocytes. In lymph nodes, the main reactivity is observed in T cell areas. Anti-CD5 is a pan T-cell marker that also reacts with a range of neoplastic B-cells, e.g. chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL), mantle cell lymphoma, and a subset (~10%) of diffuse large B-cell lymphoma. CD5 aberrant expression is useful in making a diagnosis of mature T-cell neoplasms. Note that this MAb is not suitable for frozen tissues.
Product origin	Animal
Ingredient of biological origin	Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Special handling for PI and label	Protect from light
Undated stability guarantee in PI	2 years
Stability at RT during shipping (protected from light)	Stable at room temperature or 37°C (98°F) for 7 days.
UNSPSC Commodity	41116161
UNSPSC Commodity Title	Primary and secondary antibodies for multiple methodology immunostaining detection application
Classified or regulated chemicals	0.05% sodium azide (CAS 26628-22-8)
Concentration	0.1 mg/mL
Storage buffer	PBS, 0.1% BSA, 0.05% azide
Dated shelf life printed on label	Guaranteed for at least 24 months from date of receipt when stored as recommended
Immunogen (Secondaries, for anti tag only)	T cells activated with PHA
Clonality	Monoclonal
Regulatory Status	For research use only (RUO)
Human Gene Symbol	CD5
Unigene	58685
Positive Control	293T, Ramos, or MOLT-4 Cells. Tonsil.
Antibody target cellular localization	Plasma membrane
Cell tissue expression	Lymphocytes\|T-cells
Tumor expression	Leukemia/lymphoma
Antibody applications	Functional studies (published), Flow, surface (expected), IF (expected)
Antibody application notes	Not suitable for frozen tissues\|Flow cytometry: 0.5-1 ug/million cells\|Immunofluorescence: 0.5-1 ug/mL\|Optimal dilution for a specific application should be determined by user
Expected Antibody Applications	Flow (surface) (expected)\|Functional studies (published for clone)\|IF (expected)
Manufacturer - Antibody Reactivity	CD5
Antibody number	#0995

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B-BNC940995-500-datasheet.pdf

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