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Beta-2-Microglobulin (B2M)(C21.48A1), 1mg/mL

ArtNr B-BNUM0433-50
Hersteller Biotium
Menge 50 uL
Kategorie
Typ Antibody Monoclonal
Format Liquid
Applikationen WB, FC, IF
Clon C21.48A1
Specific against Human (Homo sapiens), Primate
Host Mouse
Isotype IgG2b Kappa
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias B2M,Beta 2 microglobulin
Versandbedingung Raumtemperatur
Lieferbar
Specificity Human, Non-human primates
Manufacturer - Type
Primary
Manufacturer - Applications
Flow, intracellular (verified), IF (verified), WB (verified)
Manufacturer - Category
Primary Antibodies Only
Manufacturer - Targets
Beta-2 Microglobulin
Manufacturer - Conjugate / Tag
Purified, BSA-free
Manufacturer - Host
Mus musculus (mouse)
Shipping Temperature
Room Temperature (Next day)
Storage Conditions
Store at -10 to -35 °C|Protect fluorescent conjugates from light
Molecular Weight
12 kDa
Manufacturer - Research Area
Cancer|Immunology|Inflammation
Description
Beta-2 microglobulin is a component of the class I major histocompatibility complex (MHC I) where it functions in antigen processing and presentation. Involved in the presentation of peptide antigens to the immune system. Human Beta-2 microglobulin is expressed on many types of cells including lymphocytes, thymocytes, monocytes, granulocytes, platelets, endothelial cells, and epithelial cells. It is absent on erythrocytes. This MAb is specific to human Beta-2 microglobulin and does not react with non-human primate cells. This antibody reacts with all cell types excluding erythrocytes. The detection of Beta-2 microglobulin in body fluids has been used as a tumor marker and for monitoring patients with HIV infection.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Product origin
Animal
Ingredient of biological origin
Mus musculus (mouse)
Undated stability guarantee in PI
2 years
Stability at RT during shipping (protected from light)
Stable at room temperature or 37°C (98°F) for 7 days.
UNSPSC Commodity
41116161
UNSPSC Commodity Title
Primary and secondary antibodies for multiple methodologyimmunostaining detection application
Classified or regulated chemicals
PBS, no BSA, no sodium azide (CAS 26628-22-8)
Concentration
1 mg/mL
Storage buffer
PBS, no BSA, no azide
Dated shelf life printed on label
Guaranteed for at least 24 months from date of receipt when stored as recommended
Immunogen (Secondaries, for anti tag only)
Soluble beta 2 microglobulin
Clonality
Monoclonal
Regulatory Status
For research use only (RUO)
Human Gene Symbol
B2M
Unigene
534255
Positive Control
HL-60 or HeLa cells. Melanomas and Lymphoma. Carcinoma of Stomach, Cervix, Endometrial, Kidney or Colon.
Antibody target cellular localization
Endoplasmic reticulum|Plasma membrane|Secreted (extracellular)
Antibody applications
Flow, intracellular (verified)|IF (verified)|WB (verified)
Verified antibody applications
Flow (intracellular) (verified)|IF (verified)|WB (verified)
Antibody application notes
Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody|Immunofluorescence: 0.5-1 ug/mL|Flow Cytometry 0.5-1 ug/million cells/0.1 mL|Optimal dilution for a specific application should be determined by user
Manufacturer - Antibody Reactivity
Beta-2 Microglobulin
Antibody number
#0433

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 50 uL
Lieferbar: In stock
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