P-Cadherin (CDH3) (6A9), 1mg/mL

Primary

Primary Antibodies Only

Purified, BSA-free

Room Temperature (Next day)

116 kDa

This antibody recognizes a protein of 116 kDa, identified as P-Cadherin-1 (CDH3). It is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene have been associated with congenital hypotrichosis with juvenile macular dystrophy.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Mus musculus (mouse)

Stable at room temperature or 37°C (98°F) for 7 days.

Primary and secondary antibodies for multiple methodologyimmunostaining detection application

1 mg/mL

Guaranteed for at least 24 months from date of receipt when stored as recommended

Monoclonal

CDH3

A431 or PC-3 cells. Pancreas, Placenta or Prostate

Epithelial cells

Functional studies (published)|IF (published)|IHC, FFPE (published)|IP (published)|WB (published)

Functional studies (published for clone), IHC (FFPE) (published for clone), IF (published for clone), IP (published for clone), WB (published for clone)

#1428