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HNF1A (Pancreatic Tumor Suppressor)(HNF1A/2087), 1mg/mL

ArtNr B-BNUM2087-50
Hersteller Biotium
Menge 50 uL
Kategorie
Typ Antibody Monoclonal
Format Liquid
Applikationen IHC
Clon HNF1A/2087
Specific against Human (Homo sapiens)
Host Mouse
Isotype IgG1 Kappa
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Versandbedingung Raumtemperatur
Lieferbar
Manufacturer - Type
Primary
Manufacturer - Applications
IHC, FFPE (verified)
Manufacturer - Category
Primary Antibodies Only
Manufacturer - Targets
HNF1A
Manufacturer - Conjugate / Tag
Purified, BSA-free
Manufacturer - Host
Mus musculus (mouse)
Shipping Temperature
Room temperature
Storage Conditions
Store at -10 to -35 °C|Protect fluorescent conjugates from light
-35°C to -5°C
Molecular Weight
79 kDa
Description
HNF1A belongs to the homeobox protein family and is an essential transcription factor for many hepatic genes involved in detoxification, homeostasis and metabolisms of glucose, lipid, steroid and amino acid. In addition, HNF1A is an important component of the transcriptional networks governing embryonic pancreas development and differentiation. as well as maintaining the growth and function of islet cells in adult. HNF1A (Hepatocyte nuclear factor 1 alpha) is a transcription factor that is known to regulate pancreatic differentiation and maintain homeostasis of endocrine pancreas. Recently, genome-wide association studies have implicated HNF1Aas a susceptibility gene for pancreatic cancer. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Product origin
Animal
Ingredient of biological origin
Mus musculus (mouse)
Undated stability guarantee in PI
2 years
Stability at RT during shipping (protected from light)
Stable at room temperature or 37°C (98°F) for 7 days.
UNSPSC Commodity
41116161
UNSPSC Commodity Title
Primary and secondary antibodies for multiple methodology
immunostaining detection application
Classified or regulated chemicals
PBS, no BSA, no sodium azide (CAS 26628-22-8)
Concentration
1 mg/mL
Storage buffer
PBS, no BSA, no azide
Dated shelf life printed on label
Guaranteed for at least 24 months from date of receipt when stored as recommended
Immunogen (Secondaries, for anti tag only)
Recombinant fragment (around aa 214-339) of human HNF1A protein (exact sequence is proprietary)
Clonality
Monoclonal
Regulatory Status
For research use only (RUO)
Human Gene Symbol
HNF1A
Unigene
654455
Positive Control
Jurkat cells. Small Intestine or Pancreas.
Antibody target cellular localization
Nucleus
Validated in protein array
Monospecific
Antibody applications
IHC, FFPE (verified)
Verified antibody applications
IHC (FFPE) (verified)
Manufacturer - Synonym
Albumin proximal factor, Hepatic nuclear factor 1 alpha, Hepatic transcription factor 1 alpha, HNF-1A, Interferon production regulator factor, LFB1, LFB1 hepatic nuclear factor, Liver specific transcription factor LFB1, Maturity onset diabetes of the young 3 (MODY3), TCF1, Transcription factor 1 hepatic
Manufacturer - Antibody Reactivity
HNF1A
Antibody number
#2087

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 50 uL
Lieferbar: In stock
lieferbar

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