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Anti-EF-Ts/TSFM Antibody Picoband® Europäischer Partner

ArtNr BOS-A08656-2
Hersteller Boster
Menge 100 ug/vial
Kategorie
Typ Antibody
Format Lyophilized
Applikationen WB, ELISA
Specific against Human (Homo sapiens)
Host Rabbit
Isotype IgG
Citations 1. Ahola, S., Isohanni, P., Euro, L., Brilhante, V., Palotie, A., Pihko, H., Lonnqvist, T., Lehtonen, T., Laine, J., Tyynismaa, H., Suomalainen, A. Mitochondrial EFTs defects in juvenile-onset Leigh disease, ataxia, neuropathy, and optic atrophy. Neurology 83: 743-751, 2014.
2. Shamseldin, H. E., Alshammari, M., Al-Sheddi, T., Salih, M. A., Alkhalidi, H., Kentab, A., Repetto, G. M., Hashem, M., Alkuraya, F. S. Genomic analysis of mitochondrial diseases in a consanguineous population reveals novel candidate disease genes. J. Med. Genet. 49: 234-241, 2012.
3. Smeitink, J. A. M., Elpeleg, O., Antonicka, H., Diepstra, H., Saada, A., Smits, P., Sasarman, F., Vriend, G., Jacob-Hirsch, J., Shaag, A., Rechavi, G., Welling, B., Horst, J., Rodenburg, R. J., van den Heuvel, B., Shoubridge, E. A. Distinct clinical phenotypes associated with a mutation in the mitochondrial translation elongation factor EFTs. Am. J. Hum. Genet. 79: 869-877, 2006.
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Annexin A8 ;Annexin VIII ;Annexin-8 ;Vascular anticoagulant-beta ;VAC-beta ;ANXA8 ;ANX8;
Lieferbar
Manufacturer - Category
Primary Antibodies
Manufacturer - Isotype
Rabbit IgG
Storage Conditions
At -20°C for one year from date of receipt.
After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months.
Avoid repeated freezing and thawing.
Observed Molecular Weight
35 kDa
Calculated Molecular weight
36881 MW
Clonality
Polyclonal
Application Details
Western blot, 0.25-0.5 ?g/ml, Human

ELISA, 0.1-0.5 ?g/ml, -
Manufacturer - Gene Name
TSFM
Gene Full Name
Annexin A8
Background
Elongation factor Ts, mitochondrial is a protein that in humans is encoded by the TSFM gene. It is an EF-Ts homolog. This gene encodes a mitochondrial translation elongation factor. The encoded protein is an enzyme that catalyzes the exchange of guanine nucleotides on the translation elongation factor Tu during the elongation step of mitchondrial protein translation. Mutations in this gene are associated with combined oxidative phosphorylation deficiency-3 syndrome. Alternate splicing results in multiple transcript variants.
Immunogen
E.coli-derived human EF-Ts/TSFM recombinant protein (Position: M1-E325).
Contents
Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
Purification
Immunogen affinity purified.
Reconstitution
Adding 0.2 ml of distilled water will yield a concentration of 500 ?g/ml.
Concentration
Adding 0.2 ml of distilled water will yield a concentration of 500 ?g/ml.
Manufacturer - Research Category
Signal Transduction, Cardiovascular, Cytoskeleton, Cytoskeleton/ECM, Actin Binding Proteins, Actin, etc., Microfilaments, Cell Adhesion
Protein Name
Annexin A8
Protein Function
This protein is an anticoagulant protein that acts as an in inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade.
Subcellular Localization
Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.
Description
Boster Bio Anti-EF-Ts/TSFM Antibody Picoband® catalog # A08656-2. Tested in ELISA, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Tissue Specificity
Ubiquitously expressed.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug/vial
Lieferbar: In stock
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