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Anti-ETF/TEAD2 Antibody PicobandÂ®

Anti-ETF/TEAD2 Antibody PicobandÂ®

ArtNr	BOS-A09168-2
Hersteller	Boster
Menge	100 ug/vial
Kategorie	Antibodies Primary Antibodies
Typ	Antibody
Format	Lyophilized
Applikationen	WB, FC, IHC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Citations	1. Jacquemin, P., Depetris, D., Mattei, M.-G., Martial, J. A., Davidson, I. Localization of human transcription factor TEF-4 and TEF-5 (TEAD2, TEAD3) genes to chromosomes 19q13.3 and 6p21.2 using fluorescence in situ hybridization and radiation hybrid analysis. Genomics 55: 127-129, 1999. 2. Jacquemin, P., Hwang, J.-J., Martial, J. A., Dolle, P., Davidson, I. A novel family of developmentally regulated mammalian transcription factors containing the TEA/ATTS DNA binding domain. J. Biol. Chem. 271: 21775-21785, 1996.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Homer protein homolog 3;Homer-3;HOMER3;
Lieferbar
Manufacturer - Category	Primary Antibodies
Manufacturer - Isotype	Rabbit IgG
Storage Conditions	Store at -20Â°C for one year from date of receipt. After reconstitution, at 4Â°C for one month. It can also be aliquotted and stored frozen at -20Â°C for six months. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight	49 kDa
Calculated Molecular weight	39836 MW
Clonality	Polyclonal
Application Details	Western blot, 0.25-0.5?g/ml, Human Immunohistochemistry (Paraffin-embedded Section), 2-5?g/ml, Human, Mouse, Rat Flow Cytometry (Fixed), 1-3?g/1x10⁶ cells, Human ELISA, 0.1-0.5?g/ml, -
Manufacturer - Gene Name	TEAD2
Gene Full Name	Homer protein homolog 3
Background	TEAD2 (ETF, ETEF-1, TEF-4), together with TEAD1, defines a novel family of transcription factors, the TEAD family, highly conserved through evolution. TEAD proteins were notably found in Drosophila (Scalloped), C. elegans (egl -44), S. cerevisiae and A. nidulans. TEAD2 has been less studied than TEAD1 but a few studies revealed its role during development. TEAD2 is a member of the mammalian TEAD transcription factor family (initially named the transcriptional enhancer factor (TEF) family), which contain the TEA/ATTS DNA-binding domain.[7] Members of the family in mammals are TEAD1, TEAD2, TEAD3, TEAD4.
Immunogen	E.coli-derived human ETF/TEAD2 recombinant protein (Position: K125-M398).
Contents	Each vial contains 4 mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.01mg NaN3.
Purification	Immunogen affinity purified.
Reconstitution	Add 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ?g/ml.
Manufacturer - Research Category	Receptors / Channels, Synapse Marker
Protein Function	Postsynaptic density scaffolding protein. Binds and cross-links cytoplasmic regions of GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2, SHANK1 and SHANK3. By physically linking GRM1 and GRM5 with ER-associated ITPR1 receptors, it aids the coupling of surface receptors to intracellular calcium release. Isoforms can be differently regulated and may play an important role in maintaining the plasticity at glutamatergic synapses.
Subcellular Localization	Cytoplasm. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density. Cell junction, synapse. Postsynaptic density of neuronal cells.
Description	Boster Bio Anti-ETF/TEAD2 Antibody Picoband® catalog # A09168-2. Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Tissue Specificity	Detected in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.

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BOS-A09168-2-datasheet.pdf

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