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Rsk-1 (phospho-T359/S363) polyclonal antibody

Rsk-1 (phospho-T359/S363) polyclonal antibody

Hersteller	Bioworld Technology, Inc
Kategorie	Metabolism Cholesterol & Lipid Metabolism Antibodies Immunoprecipitation Western Blot Cardiovascular Research Enzymes Fatty Acid Catabolism Hypertension Primary Antibodies
Typ	Antibody Primary
Specific against	Human, Mouse, Rat
Applikationen	WB, IP
Menge	100ul
Host	Rabbit
ArtNr	BS4276-100
Targets	RPS6 ;;ADRA1D;;SPHK1
eClass 6.1	32160702
eClass 9.0	32160702
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Swiss-Prot	Q15418
Application_all	WB: 1:500ca.1:1000 IP: 1:50ca.1:200
Background	The family of ribosomal S6 kinases (Rsks), designated Rsk-1 (or MAPKAP kinase-1), Rsk-2 and Rsk-3, are intracellular serine/threonine kinases that are important signaling intermediates in response to a broad range of ligand activated receptor tyrosine kinases. A unique feature common to the members of the Rsk family is that each possesses two non-identical complete kinase catalytic domains. An additional Rsk protein, Rsk-4, shows a high level of homology to the three previously isolated members of the human Rsk family. Rsk-4 is most abundantly expressed in brain and kidney and plays a role in normal neuronal development.
Product	Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification And Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage And Stability	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Specificity	Rsk-1 (phospho-T359/S363) polyclonal antibody detects endogenous levels of Rsk-1 protein only when phosphorylated at Thr359/Ser363.
BiowMW	ca. 90 kDa
Note	For research use only, not for use in diagnostic procedure.
Immunogen	Synthetic phosphopeptide derived from human Rsk-1 around the phosphorylation site of Thr359/Ser363.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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