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CDK7 (Phospho-T170) polyclonal antibody

CDK7 (Phospho-T170) polyclonal antibody

Hersteller	Bioworld Technology, Inc
Kategorie	Neuroscience Neural Lineage Markers Neural Transcription Factors Molecular Targets for Neuroscience Antibodies Cell Biology Cell Status Immunohistochemistry Western Blot Proliferation Primary Antibodies
Typ	Antibody Primary
Specific against	Human, Mouse
Applikationen	WB, IHC
Menge	100ul
Host	Rabbit
ArtNr	BS64520-100
Targets	CDK7;;GTF2H1;;PCNA
eClass 6.1	32160702
eClass 9.0	32160702
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Swiss-Prot	P50613
Application_all	WB: 1:500ca.1:1000 IHC: 1:50ca.1:200
Background	Cdk7 is a member of the cyclin dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. Cdk7 forms a trimeric complex with cyclin H and MAT1, which functions as a Cdk activating kinase (CAK). It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. This protein is thought to serve as a direct link between the regulation of transcription and the cell cycle.
Product	Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification And Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage And Stability	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Specificity	CDK7 (Phospho-T170) polyclonal antibody detects endogenous levels of CDK7 protein only when phosphorylated at Thr170.
BiowMW	ca. 40 kDa
Note	For research use only, not for use in diagnostic procedure.
Immunogen	Synthetic phosphopeptide derived from human CDK7 around the phosphorylation site of Threonine 170.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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