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PKCbeta1 polyclonal antibody

Hersteller Bioworld Technology, Inc
Kategorie
Typ Antibody Primary
Specific against Human, Mouse, Rat
Applikationen WB, FC, IHC
Menge 50ul
Host Rabbit
ArtNr BS91082-50
Targets MOG ;;PRKCB
eClass 6.1 32160702
eClass 9.0 32160702
Lieferbar
Swiss-Prot
P05771(Human) P68404(Mouse) P68403(Rat)
Application_all
WB:1:500 IHC:1:50-1:200 FC:1:50-1:100
Background
Members of the protein kinase C (PKC) family play a key regulatory role in a variety of cellular functions, including cell growth and differentiation, gene expression, hormone secretion and membrane function. PKCs were originally identified as serine/threonine protein kinases whose activity was dependent on calcium and phospholipids. Diacylglycerols (DAG) and tumor promoting phorbol esters bind to and activate PKC. PKCs can be subdivided into at least two major classes, including conventional (c) PKC isoforms (alpha, betaI, betaII and gamma) and novel (n) PKC isoformsandny. Patterns of expression for each PKC isoform differ among tissues and PKC family members exhibit clear differences in their cofactor dependencies. For instance, the kinase activities of PKC delta and epsilon are independent of Ca2+. On the other hand, most of the other PKC members possess phorbol ester-binding activities and kinase activities.
Product
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification And Purity
ProA affinity purified
Storage And Stability
Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.
Specificity
PKCbeta1 polyclonal antibody detects endogenous levels of PKCbeta1 protein.
BiowMW
77 kDa
Note
For research use only, not for use in diagnostic procedure.
Immunogen
Recombinant protein

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 50ul
Lieferbar: In stock
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