Tubulingamma polyclonal antibody

P23258(Human) Q9NRH3(Human) P83887(Mouse) Q8VCK3(Mouse) P83888(Rat) P23330(Xenopus laevis)

Tubulin is a major cytoskeleton component that has five distinct forms, designated alpha, beta, gamma, delta and e Tubulin. alpha and beta Tubulins form heterodimers which multimerize to form a microtubule filament. Multiple beta Tubulin isoforms (beta1, beta2, beta3, beta4, beta5, beta6 and beta8) have been characterized and are expressed in mammalian tissues. beta1 and beta4 are present throughout the cytosol, beta2 is present in the nuclei and nucleoplasm, and beta3 is a neuron-specific cytoskeletal protein. gamma Tubulin forms the gammasome, which is required for nucleating microtubule filaments at the centrosome. Both delta Tubulin and e Tubulin are associated with the centrosome. delta Tubulin is a homolog of the Chlamydomonas delta Tubulin Uni3 and is found in association with the centrioles, whereas e Tubulin localizes to the pericentriolar material. e Tubulin exhibits a cell-cycle-specific pattern of localization, first associating with only the older of the centrosomes in a newly duplicated pair and later associating with both centrosomes.

ProA affinity purified

Tubulingamma polyclonal antibody detects endogenous levels of Tubulingamma protein.

For research use only, not for use in diagnostic procedure.