VCP polyclonal antibody

P55072(Human) Q01853(Mouse) P46462(Rat)

Valosin containing protein (VCP), also designated TERA (for transitional endoplasmic reticulum ATPase) or p97, is a member of the AAA family of ATPases, which are involved in a variety of cellular activities. VCP is the mammalian homolog of Saccharomyces cerevisiae Cdc48, a protein essential for the completion of mitiosis in yeast. VCP is thought to be involved in a variety of membrane functions and in the regulation of the cell cycle. It associates with ubiquitinated IkappaB-alpha as well as with the 26S Proteosome, indicating a potential role for VCP in the proteosome-mediated degradation of IkappaB-alpha.

ProA affinity purified

VCP polyclonal antibody detects endogenous levels of VCP protein.

For research use only, not for use in diagnostic procedure.