EBI3 antibody

ArtNr	FNab02615-100ug
Hersteller	FineTest
Menge	100 ug
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Monoclonal
Format	Liquid
Applikationen	WB, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Purity	≥95% as determined by SDS-PAGE
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Interleukin-27 subunit beta (IL-27 subunit beta,IL-27B),Epstein-Barr virus-induced gene 3 protein (EBV-induced gene 3 protein),EBI3,IL27B
Lieferbar
Manufacturer - Targets	EBI3
Storage Conditions	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
Background	Associates with IL27 to form the IL-27 interleukin, a heterodimeric cytokine which functions in innate immunity. IL-27 has pro-and anti-inflammatory properties, that can regulate T-helper cell development, suppress T-cell proliferation, stimulate cytotoxic T-cell activity, induce isotype switching in B-cells, and that has diverse effects on innate immune cells. Among its target cells are CD4 T-helper cells which can differentiate in type 1 effector cells(TH1), type 2 effector cells(TH2) and IL17 producing helper T-cells(TH17). It drives rapid clonal expansion of naive but not memory CD4 T-cells. It also strongly synergizes with IL-12 to trigger interferon-gamma/IFN-gamma production of naive CD4 T-cells, binds to the cytokine receptor WSX-1/TCCR. Another important role of IL-27 is its antitumor activity as well as its antiangiogenic activity with activation of production of antiangiogenic chemokines.
Clonality	polyclonal
Immunogen	Epstein-Barr virus induced 3
Observed MW	25-35 kDa
Purification	Immunogen affinity purified
Recommended dilution	WB: 1:500-1:2000
Manufacturer - Research Area	Immunology, Signal Transduction, Developmental biology

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