Vergleich

Anti-Mouse CD278 (ICOS) - Biotin - 50 µg

ArtNr LEIN-C2259-50ug
Hersteller Leinco Technologies
Menge 50 ug
Kategorie
Typ Antibody Monoclonal
Applikationen FC
Clon 7E.17G9
Specific against Mouse (Murine, Mus musculus)
Host Rat
NCBI 54167
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Category
Primary Monoclonal Antibodies>Immune Checkpoints|Primary Monoclonal Antibodies>Surfacetag Mouse CD Markers
Manufacturer - Targets
CD278
Shipping Temperature
Next Day 2 - 8°C
Storage Conditions
This biotinylated antibody is stable when stored at 2-8°C. Do not freeze.
Product Description
CD278 (ICOS) belongs to the CD28 and CTLA-4 cell-surface receptor family. It forms homodimers (47-57kD) and enhances all basic T cell responses to a foreign antigen, specifically proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B cells. ICOS signaling is also an important regulator for T cell homeostasis. ICOS plays a role in humoral immune response and is thought to have involvement in the development of Th2 cells and to play a protective role in inflammatory autoimmune diseases.
Background
CD278 (ICOS) belongs to the CD28 and CTLA-4 cell-surface receptor family. It forms homodimers (47-57kD) and enhances all basic T cell responses to a foreign antigen, specifically proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B cells. ICOS signaling is also an important regulator for T cell homeostasis. ICOS plays a role in humoral immune response and is thought to have involvement in the development of Th2 cells and to play a protective role in inflammatory autoimmune diseases.
PubMed
CD278
Ligand/Receptor
B7h/B7RP-1/GL-50
Manufacturer - Research Area
Costimulatory Molecules, Immunology
Manufacturer - Specificity
Clone 7E.17G9 recognizes an epitope on mouse CD278.
RRID
AB_2829345
Concentration
0.5 mg/ml
Formulation
This biotinylated antibody is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative.
Antigen Distribution
ICOS is expressed on activated T cells and APCs including splenic B cells, dendritic cells, and macrophages.
Immunogen
Purified Recombinant Mouse ICOS
Additional Information
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.
Keywords
Monoclonal Antibody, CD278, Inducible Costimulator, 7E.17G9, ICOS, Mouse, Anti-Mouse CD278 (ICOS) - Biotin

Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.

Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 50 ug
Lieferbar: In stock
lieferbar

Vergleichen

Auf den Wunschzettel

Angebot anfordern

Lieferzeit anfragen

Technische Frage stellen

Bulk-Anfrage stellen

Fragen zum Produkt?
 
Schließen