Anti-Mouse CD32/CD16 - Purified (PhenoCyler-Fusion (CODEX)® Ready) - 50 µg

Monoclonal Antibodies|PhenoCycler®>PhenoCycler® Validated Antibodies|Primary Monoclonal Antibodies>Surfacetag Mouse CD Markers

Next Day Ambient

CD16 is expressed in two forms: CD16a and CD16b. CD16a (FcγRIIIA) is a 50-65 kD polypeptide-anchored transmembrane protein. CD16b (FcγRIIIB) is a 48 kD GPI-anchored protein whose extracellular domain is over 95% homologous to that of CD16a. CD16 regulates both phagocytosis and antibody-dependent cell-mediated cytotoxicity. It has been reported that CD16 is involved in Natural Killer Cell activation and plays a role in signal transduction. The receptors, CD32 (FcγRIII) and CD16 (FcγRII), are 40-60 kD and bind antibody-antigen immune complexes and mediate adaptive immune responses.

0.5 mg/ml

These receptors are present on B cells, monocyte/macrophages, NK cells, neutrophils, mast cells and dendritic cells.