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Anti-Human IL-16 - Biotin - 50 µg

ArtNr LEIN-I-271-50ug
Hersteller Leinco Technologies
Menge 50 ug
Kategorie
Typ Antibody Primary
Applikationen WB, FC, ELISA
Specific against Human (Homo sapiens)
Host Caprine
NCBI 3603
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Versandbedingung Raumtemperatur
Lieferbar
Manufacturer - Applications
ELISA Det, FC, WB
Manufacturer - Category
Polyclonal Antibodies>Biotin Growth Factors & Cytokines
Manufacturer - Targets
IL-16
Country of Origin
USA
Shipping Temperature
Next Day Ambient
Storage Conditions
The lyophilized, biotinylated antigen affinity purified polyclonal antibody can be stored desiccated at -20°C to -70°C for up to twelve months from date of receipt. The reconstituted biotin conjugate can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted conjugate, aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. No detectable loss of activity was observed after six months.
Product Description
IL-16 is a CD8+ T cell-derived cytokine that induces chemotaxis of CD4+ T cells and CD4+ monocytes and eosinophils. Analysis by gel filtration suggests that, under physiological conditions, hIL-16 exists predominantly as a noncovalently linked multimer, but that some IL-16 may exist as a monomer. However, only the multimeric form appears to possess chemotactic activity, suggesting that receptor cross-linking may be required for activity. IL-16 also induces expression of IL-2 receptor (IL-2R) and MHC class II molecules on CD4 + T cells. Human and mouse IL-16 show significant cross-species reactivity.
Background
IL-16 is a CD8+ T cell-derived cytokine that induces chemotaxis of CD4+ T cells and CD4+ monocytes and eosinophils. Analysis by gel filtration suggests that, under physiological conditions, hIL-16 exists predominantly as a noncovalently linked multimer, but that some IL-16 may exist as a monomer. However, only the multimeric form appears to possess chemotactic activity, suggesting that receptor cross-linking may be required for activity. IL-16 also induces expression of IL-2 receptor (IL-2R) and MHC class II molecules on CD4 + T cells. Human and mouse IL-16 show significant cross-species reactivity.
PubMed
IL-16
Manufacturer - Specificity
Goat Anti-Human Interleukin-16 (IL-16) recognizes Human IL-16. This antigen affinity purified polyclonal antibody was purified using a proprietary chromatographic technique that includes covalently immobilizing the antigen proteins or peptides to agarose based beads. This purification method enhances specificity, reduces nonspecific binding of extraneous IgG and provides you with the most reliable reagent available for your early discovery research.
RRID
AB_2830615
Formulation
This biotinylated antigen affinity purified polyclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco’s phosphate buffered saline (1X PBS) pH 7.2 – 7.4 containing 50 µg of bovine serum albumin per µg of antibody with no calcium, magnesium, or preservatives present.
Immunogen
E. coli-Derived Recombinant Human Interleukin-16 Isoform 1, C-Terminal Peptide (Accession # Q14005)
Additional Information
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.
Keywords
Polyclonal Antibody, FLJ16806, FLJ42735, FLJ44234, HsT19289, IL16, IL-16, interleukin 16, LCF, LCFprIL-16, lymphocyte chemoattractant factor, neuronal interleukin 16, NIL16, PRIL16, prointerleukin 16, pro-interleukin-16, IL 16, FLJ16806, FLJ42735, FLJ44234, HsT19289, IL16, IL-16, interleukin 16 (lymphocyte chemoattractant factor), LCF, LCFprIL-16, lymphocyte chemoattractant factor, neuronal interleukin 16, NIL16, PRIL16, prointerleukin 16, pro-interleukin-16

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 50 ug
Lieferbar: In stock
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