Anti-Rat IFNγ (Clone 88915) - 100 µg

ArtNr	LEIN-I-683-100ug
Hersteller	Leinco Technologies
Menge	100 ug
Quantity options	100 ug 25 ug 500 ug
Kategorie	Antibodies Western Blot Primary Antibodies
Typ	Antibody Monoclonal
Applikationen	WB
Clon	88915
Specific against	Rat (Rattus norvegicus)
Host	Mouse
Citations	1. Goeddel, DV. et al. (1982) Nature 298: 859 2. Wilson, CB. et al. (2007) Adv. Immunol. 96: 41 3. Hume, DA. et al. (2004) J Leukoc Biol. 75: 163
NCBI	25712
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Versandbedingung	Raumtemperatur
Lieferbar
Manufacturer - Applications	N, WB
Manufacturer - Category	Primary Monoclonal Antibodies>Growth Factors and Cytokines
Manufacturer - Targets	IFNγ
Country of Origin	USA
Shipping Temperature	Next Day Ambient
Storage Conditions	The lyophilized antibody can be stored desiccated at -20°C to -70°C for up to twelve months. The reconstituted antibody can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted antibody, aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid repeated freeze thaw cycles. No detectable loss of activity was observed after six months.
Product Description	Interferon-gamma (IFN-γ) or type II interferon is a dimerized soluble cytokine that is the only member of the type II class of interferons.1 It is a cytokine critical for innate and adaptive immunity against viral and intracellular bacterial infections and for tumor control. IFNG is produced predominantly by natural killer (NK) and natural killer T (NKT) cells as part of the innate immune response, and by CD4 and CD8 cytotoxic T lymphocyte (CTL) effector T cells once antigen-specific immunity develops.2 IFN-γ has antiviral, immunoregulatory, and anti-tumour properties.3
Background	Interferon-gamma (IFN-γ) or type II interferon is a dimerized soluble cytokine that is the only member of the type II class of interferons.¹ It is a cytokine critical for innate and adaptive immunity against viral and intracellular bacterial infections and for tumor control. IFNG is produced predominantly by natural killer (NK) and natural killer T (NKT) cells as part of the innate immune response, and by CD4 and CD8 cytotoxic T lymphocyte (CTL) effector T cells once antigen-specific immunity develops.² IFN-γ has antiviral, immunoregulatory, and anti-tumour properties.³
Other Applications Reported In Literature	Neutralization: This antibody is useful for neutralization of Rat IFN-γ bioactivity. The antibody dose required to neutralize 50% (ND₅₀) of the biological activity of Rat IFN-γ (at 2.5 ng/ml) is 0.5 - 1.5 µg/ml.
PubMed	IFN gamma
Manufacturer - Research Area	Other Molecules
Manufacturer - Specificity	Mouse Anti-Rat Interferon Gamma (IFN-γ) (Clone 88915) recognizes an epitope on Rat IFN-γ. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype. This antibody shows less than 1% cross-reactivity with rmIFN-γ and no cross-reactivity rhIFN-γ.
RRID	AB_2830804
Formulation	This monoclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco's phosphate buffered saline (1X PBS) pH 7.2 - 7.3 containing 5.0% w/v trehalose with no calcium, magnesium or preservatives present.
Endotoxin Level	< 0.1 EU/µg as determined by the LAL method
Immunogen	E. coli-Derived Recombinant Rat Interferon-γ
Additional Information	Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.
Keywords	Monoclonal Antibody, Interferon Gamma, Immune Interferon, Type II Interferon, T Cell Interferon, MAF, IFNG, IFG, IFI, 88915, IFN-γ, Rat, Anti-Rat IFN-γ, IFG, IFI, IFNG, IFNgamma, IFN-gamma, Immune interferon, interferon gamma, interferon, gamma

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LEIN-I-683-100ug-safety-datasheet.pdf