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Anti-Human CD52 (Alemtuzumab) - APC - 50 µg

Anti-Human CD52 (Alemtuzumab) - APC - 50 µg

ArtNr	LEIN-LT203-50ug
Hersteller	Leinco Technologies
Menge	50 ug
Kategorie	Oncology Antibodies By Cell Type Hematology Leukemia Lymphoma Flow Cytometry Immunohistochemistry Primary Antibodies Functional Assays
Typ	Antibody Monoclonal
Applikationen	FC, IHC, FA
Clon	Campath-1H
Specific against	Human (Homo sapiens), Monkey (Cynomolgus, Simian), Rhesus macaque
Host	Human
NCBI	1043
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Applications	FA, FC, IHC FF, IHC FFPE
Manufacturer - Category	Recombinant Antibodies>Biosimilar Recombinant Antibodies
Manufacturer - Targets	CD52
Country of Origin	USA
Shipping Temperature	Next Day 2 - 8°C
Storage Conditions	This Allophycocyanin (APC) conjugate is stable when stored at 2-8°C. Do not freeze.
Product Description	Clone Campath-1H is a monoclonal antibody that specifically binds to CD52, a protein present on the surface of mature lymphocytes. However, this protein is not present on the stem cells that generated these lymphocytes. Alemtuzumab is targets and destroys mature lymphocytes containing CD-52, and is used to treat chronic lymphocytic leukemia (CLL) and multiple sclerosis. Anti-Human CD52 (Alemtuzumab) utilizes the same variable regions from the therapeutic antibody Alemtuzumab making it ideal for research projects.
Background	Clone Campath-1H is a monoclonal antibody that specifically binds to CD52, a protein present on the surface of mature lymphocytes. However, this protein is not present on the stem cells that generated these lymphocytes. Alemtuzumab is targets and destroys mature lymphocytes containing CD-52, and is used to treat chronic lymphocytic leukemia (CLL) and multiple sclerosis. Anti-Human CD52 (Alemtuzumab) utilizes the same variable regions from the therapeutic antibody Alemtuzumab making it ideal for research projects.
Additional Reported Applications For Relevant Conjugates	CyTOF® WB
Other Applications Reported In Literature	IHC FFPE (Formalin-fixed paraffin-embedded tissue) IHC FF (Fresh Frozen) FA
PubMed	CD52
Excitation Laser	Red Laser (650 nm)
Manufacturer - Research Area	Biosimilars
Manufacturer - Expression host	HEK-293
Manufacturer - Specificity	This non-therapeutic biosimilar antibody uses the same variable region sequence as the therapeutic antibody Alemtuzumab. Clone Campath-1H recognizes human CD52. This product is for research use only.
FC Effector Activity	Active
RRID	AB_2893941
Concentration	0.2 mg/ml
Formulation	This Allophycocyanin (APC) conjugate is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative.
Antigen Distribution	CD52 is primarily expressed on the surface of mature lymphocytes. Additionally, CD52 is present on most lymphoid derived malignancies. However, variable expression on Myeloma cells should be noted.
Immunogen	Human lymphocytes.
Regulatory Status	Research Use Only (RUO). Non-Therapeutic.
Additional Information	Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.
Keywords	HE5; CDW52; EDDM5 CDW52; Cambridge pathology 1 antigen; Epididymal secretory protein E5; Human epididymis-specific protein 5; YTH66.9HL; Alemtuzumab; Biosimilar

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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LEIN-LT203-50ug-safety-datasheet.pdf