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Anti-Human MIP-1β - Biotin - 50 µg

ArtNr LEIN-M193-50ug
Hersteller Leinco Technologies
Menge 50 ug
Kategorie
Typ Antibody Primary
Applikationen WB, ICC, ELISA
Specific against Human (Homo sapiens)
Host Caprine
NCBI 6351
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Versandbedingung Raumtemperatur
Lieferbar
Manufacturer - Applications
ELISA Det, ICC, WB
Manufacturer - Category
Polyclonal Antibodies>Biotin Growth Factors & Cytokines
Manufacturer - Targets
MIP-1β
Country of Origin
USA
Shipping Temperature
Next Day Ambient
Storage Conditions
The lyophilized, biotinylated antigen affinity purified polyclonal antibody can be stored desiccated at -20°C to -70°C for up to twelve months from date of receipt. The reconstituted biotin conjugate can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted conjugate, aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. No detectable loss of activity was observed after six months.
Product Description
Both MIP-1 alpha and MIP-1 beta are structurally and functionally related CC chemokines. They participate in the host response to invading bacterial, viral, parasite and fungal pathogens by regulating the trafficking and activation state of selected subgroups of inflammatory cells e.g. macrophages, lymphocytes and NK cells. While both MIP-1 alpha and MIP-1 beta exert similar effects on monocytes their effect on lymphocytes differ; with MIP-1 alpha selectively attracting CD8+ lymphocytes and MIP-1 beta selectively attracting CD4+ lymphocytes. Additionally, MIP-1 alpha and MIP-1 beta have also been shown to be potent chemoattractants for B cells, eosinophils and dendritic cells.
Background
Both MIP-1 alpha and MIP-1 beta are structurally and functionally related CC chemokines. They participate in the host response to invading bacterial, viral, parasite and fungal pathogens by regulating the trafficking and activation state of selected subgroups of inflammatory cells e.g. macrophages, lymphocytes and NK cells. While both MIP-1 alpha and MIP-1 beta exert similar effects on monocytes their effect on lymphocytes differ; with MIP-1 alpha selectively attracting CD8+ lymphocytes and MIP-1 beta selectively attracting CD4+ lymphocytes. Additionally, MIP-1 alpha and MIP-1 beta have also been shown to be potent chemoattractants for B cells, eosinophils and dendritic cells.
Other Applications Reported In Literature
Immunocytochemistry: Suitable for use at concentration of5-15 µg/mL.
PubMed
MIP-1β
Manufacturer - Specificity
Rabbit Anti-Human Macrophage Inflammatory Protein-1β (MIP-1β) recognizes Human Macrophage Inflammatory Protein-1β. This antigen affinity purified polyclonal antibody was purified using immobilized antigen agarose chromotography.
RRID
AB_2831370
Formulation
This biotinylated antigen affinity purified polyclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco’s phosphate buffered saline (1X PBS) pH 7.2 – 7.4 containing 50 µg of bovine serum albumin per µg of antibody with no calcium, magnesium, or preservatives present.
Immunogen
Purified Recombinant Human MIP-1β (> 98%)
Additional Information
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.
Keywords
Polyclonal Antibody, MIP-1β, CCL4, ACT2, AT744.1, G-26, LAG1, MGC104418, MGC126025, MGC126026, MIP1B1, SCYA2, SCYA4, MIP-1β, Human, Anti-Human MIP-1β-Biotin, Human MIP 1β, MIP 1β, ACT2, ACT-2, AT744.1, C-C motif chemokine 4, CCL4, chemokine (C-C motif) ligand 4, Exodus-3, G-26 T-lymphocyte-secreted protein, G-26, HC21, LAG1, LAG-1, Lymphocyte activation gene 1 protein, Macrophage inflammatory protein 1-beta, MIP1 beta, MIP-1 beta, MIP1B, MIP1B1, MIP-1-beta, MIP-1-beta(1-69), PAT 744, Protein H400, SCYA2, SCYA4, secreted protein G-26, SIS-gamma, small inducible cytokine A4 (homologous to mouse Mip-1b), Small-inducible cytokine A4, T-cell activation protein 2

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 50 ug
Lieferbar: In stock
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