Anti-Human p34^cdc2 Serine/Threonine Kinase Purified - 0.25 mg

IHC FFPE, WB

p34cdc2 Serine/Threonine Kinase

Next Day 2 - 8°C

p34cdc2 is thought to be activated by cyclin through dephosphorylation at tyrosine residues. Activated p34cdc2 kinase is involved in a number of mitotic events such as nuclear envelope breakdown and chromosome condensation through phosphorylation of serine/threonine residues of substrates such as nuclear lamins, histones, pp60c-src, nucleolin and RNA polymerase II. It is then inactivated by a tyrosine kinase. Anti-p34cdc2 can be used in western blotting, immunoprecipitation and immunohistochemistry. The antibody precipitates an active kinase.

p34cdc2 Serine/Threonine Kinase

Mouse Anti-Human p34^cdc2 Serine/Threonine Kinase (p34^cdc2 Serine/Threonine Kinase) (Clone 17) recognizes an epitope on Human p34^cdc2 Serine/Threonine Kinase near the C-terminus in human, mouse, or xenopus cells. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

0.5 mg/ml

Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.