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anti-STAT1 - Purified - 100 µg

ArtNr LEIN-S652-100ug
Hersteller Leinco Technologies
Menge 100 ug
Kategorie
Typ Antibody Monoclonal
Applikationen WB
Clon 10C4B40
Specific against Human (Homo sapiens)
Host Mouse
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Applications
Quality Tested by Leinco WB To detect Human STAT1 this monoclonal antibody can be used at a concentration of 0.5 - 2.5 µg per ml. It is recommended that the reagent be titrated for optimal performance for each application.
Manufacturer - Category
Primary Monoclonal Antibodies>Apoptosis & Cell Biology|Primary Monoclonal Antibodies>Tumor Markers
Manufacturer - Targets
STAT1
Country of Origin
USA
Shipping Temperature
Next Day 2 - 8°C
Storage Conditions
This Purified conjugate is stable when stored at 2-8°C. Do not freeze.
Product Description
STAT1, also known as signal transduction and activator of transcription 1, is a ubiquitously expressed cytoplasmic protein and is activated in response to cytokine signaling, including IFN-α, IFN-γ, EGF, PDGF, and IL-6. Upon activation, STAT1 is phosphorylated by receptor-associated kinases, translocates to the nucleus, and functions as a transcription factor.
Background
STAT1, also known as signal transduction and activator of transcription 1, is a ubiquitously expressed cytoplasmic protein and is activated in response to cytokine signaling, including IFN-α, IFN-γ, EGF, PDGF, and IL-6. Upon activation, STAT1 is phosphorylated by receptor-associated kinases, translocates to the nucleus, and functions as a transcription factor.
PubMed
STAT1
Manufacturer - Specificity
Mouse Anti-STAT1 (Clone 10C4B40) recognizes an epitope on Human STAT1. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
RRID
AB_2831816
Concentration
0.5 mg/ml
Formulation
This Purified conjugate is formulated in 0.01 M phosphate buffered saline (PBS) pH 7.2 - 7.4, 150 mM NaCl, 1% BSA and 0.09% sodium azide as a preservative.
Antigen Distribution
Cytoplasm; phosphorylated form translocated to the nucleus.
Additional Information
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.
Keywords
Monoclonal Antibody, STAT1, Signal transducer and activator of transcription 1 (STAT1), Transcription factor ISGF-3 components p, 10C4B40, anti-STAT1 - Purified, STAT1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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