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Anti-TGF-β1 - Biotin - 50 µg

Anti-TGF-β1 - Biotin - 50 µg

ArtNr	LEIN-T480-50ug
Hersteller	Leinco Technologies
Menge	50 ug
Kategorie	Antibodies Western Blot ELISA Primary Antibodies Immunostaining
Typ	Antibody Primary
Applikationen	WB, ELISA
Specific against	Human (Homo sapiens)
Host	Chicken
Citations	1. Guven, M. et al. (2007) Growth Factors 25: 101 2. Schneider, J. et al. (2009) J Investing Med. 57(5):655-61 3. Yu, C. et al. (2009) Biochem Biophys Res Commun. 406(2):204-210
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Versandbedingung	Raumtemperatur
Lieferbar
Manufacturer - Applications	ELISA Det, WB
Manufacturer - Category	Polyclonal Antibodies>Biotin Growth Factors & Cytokines
Manufacturer - Targets	TGF-β1
Country of Origin	USA
Shipping Temperature	Next Day Ambient
Storage Conditions	The lyophilized, biotinylated antigen affinity purified polyclonal antibody can be stored desiccated at -20°C to -70°C for up to twelve months from date of receipt. The reconstituted biotin conjugate can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted conjugate, aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. No detectable loss of activity was observed after six months.
Product Description	Transforming growth factor beta 1 or TGF-β1 is a multifunctional cytokine that regulates the proliferation and differentiation of cells specific to bone like chondrocytes, osteoblasts, osteoclasts including mesenchymal precursor cells.1 It is known to promote the pathogenesis of lung fibrosis and acts as a tumor suppressor in normal cells.2 TGF-beta1 can promote mechanical strength in healing Achilles tendons by regulating collagen synthesis, cross-link formation, and matrix remodeling.3
Background	Transforming growth factor beta 1 or TGF-β1 is a multifunctional cytokine that regulates the proliferation and differentiation of cells specific to bone like chondrocytes, osteoblasts, osteoclasts including mesenchymal precursor cells.¹ It is known to promote the pathogenesis of lung fibrosis and acts as a tumor suppressor in normal cells.² TGF-beta1 can promote mechanical strength in healing Achilles tendons by regulating collagen synthesis, cross-link formation, and matrix remodeling.³
PubMed	TGF-β1
Manufacturer - Specificity	Chicken Anti-Human Transforming Growth Factor Beta 1 (TGF-β1) recognizes Human TGF-β1. This antigen affinity purified polyclonal antibody was purified using a proprietary chromatographic technique that includes covalently immobilizing the antigen proteins or peptides to agarose based beads. This purification method enhances specificity, reduces nonspecific binding of extraneous IgG and provides you with the most reliable reagent available for your early discovery research.
RRID	AB_2831980
Formulation	This biotinylated antigen affinity purified polyclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco’s phosphate buffered saline (1X PBS) pH 7.2 – 7.4 containing 50 µg of bovine serum albumin per µg of antibody with no calcium, magnesium, or preservatives present.
Immunogen	Purified Recombinant Human TGF-β1 (> 98%)
Additional Information	Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.
Keywords	Polyclonal Antibody, Transforming Growth Factor-Beta 1, TGFB, TGFB1, Differentiation Inhibiting Factor, Cartilage-Inducing Factor, Latency Associated Peptide, CED, TGF-β1, Human TGFb, Anti-TGFβ1, CEDLAP, latency-associated peptide, TGF-beta 1 protein, TGFbeta 1, TGF-be, CEDLAP, DPD1, latency-associated peptide, TGFB, TGFB1, TGF-beta 1 protein, TGFbeta 1, TGF-beta 1, TGFbeta, TGF-beta-1, transforming growth factor beta-1, transforming growth factor, beta 1

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LEIN-T480-50ug-safety-datasheet.pdf