TMPRSS2 Antibody [ARC2373]

Primary Antibodies

Store at 4˚ C short term. Aliquot and store at -20˚ C long term. Avoid freeze-thaw cycles.

This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a type II transmembrane domain, a receptor class A domain, a scavenger receptor cysteine-rich domain and a protease domain. Serine proteases are known to be involved in many physiological and pathological processes. This gene was demonstrated to be up-regulated by androgenic hormones in prostate cancer cells and down-regulated in androgen-independent prostate cancer tissue. The protease domain of this protein is thought to be cleaved and secreted into cell media after autocleavage. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]

NONE

batch dependent

WB: 1:500 - 1:2000, IHC: 1:50 - 1:200

Monoclonal

Homo sapiens

Optimal dilutions for each application to be determined by the researcher.