Hersteller |
NKMAX
|
Kategorie |
|
Typ |
Antibody Monoclonal |
Specific against |
Human |
Clon |
AT5F4 |
Isotype |
IgG2b kappa |
Applikationen |
WB, IF, ICC, ELISA |
Menge |
100ul |
Host |
Mouse |
ArtNr |
NKM-ATGA0585-100ul |
Konjugat/Tag |
Unconjugated |
eClass 6.1 |
32160702 |
eClass 9.0 |
42030590 |
Lieferbar |
|
Ab Purification Comment |
By protein-A affinity chromatography |
Additional Comment Only |
This product was produced from tissue culture supe |
Antigen Species |
Human |
Concentration |
1mg/ml (determined by BCA assay) |
Description |
Non-metastatic cells 1 (NME1), also known as NM23-H1, originally identified as a candidate metastasis suppressor gene. NME1 is expressed in different tumor types where their levels have been alternatively associated with reduced or increased metastatic potential. Reductions in NME1 expression have been significantly associated with aggressive behavior in melanoma, breast, colon, and gastric carcinomas. On the contrary, high levels of NME1 gene expression are noted in the advanced stage of thyroid carcinomas. |
Formulation |
Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol |
Gene Category |
Epigenetics and Nuclear Signaling |
General References |
Tee YT., et al. (2006) Taiwan J Obstet Gynecol. 45(2): 107-13.; ; Negroni A., et al. (2000) Cell Death Differ. 7(9): 843-50. |
Immunogen |
Recombinant human NME1 (1-152aa) purified from E. coli |
Storage |
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles. |
Usage |
The antibody has been tested by ELISA, Western blot and ICC/IF analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. |
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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.