SARS-COV-2 Nucleocapsid Protein Antibody [9A4B3]

Rabbit IgG

2˚ C - 8˚ C for one month, -20˚ C to -80˚ C for one year. Avoid repeated freeze-thaw cycles

Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.

Recombinant

Affinity purification

< 1.0 EU/ug of the protein by LAL method.

Lyophilized from a 0.2 um filtered solution in PBS, pH7.4 with antibody at a final concentration of 1 mg/ml.

SARS-COV-2

Recombinant Monoclonal

SARS-CoV-2

Optimal dilutions for each application to be determined by the researcher.