FLNA Antibody [A0F7]

ArtNr	PRS-13-840-50uL
Hersteller	ProSci
Menge	50 uL
Kategorie	Antibodies Cell Biology Cell Movement Immunohistochemistry Western Blot Immunofluorescence Cardiovascular Research Thrombosis & Hemostasis Atherosclerosis Primary Antibodies Cell Migration & Invasion
Typ	Antibody Primary
Format	Liquid
Applikationen	WB, IF, IHC
Clon	A0F7
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
NCBI	FLNA
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	FLNA, filamin A, alpha, ABP-280, ABPX, CVD1, FLN, FLN-A, FLN1, FMD, MNS, NHBP, OPD, OPD1, OPD2, XLVD, XMVD, actin binding protein 280, alpha-filamin, endothelial actin-binding protein, filamin-1, filamin-A, non-muscle filamin
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Manufacturer - Applications	WB: 1:500 - 1:2000 IHC: 1:50 - 1:100 IF: 1:50 - 1:100
Shipping Temperature	blue ice or room temperature
Storage Conditions	Store at -20°C. Avoid freeze / thaw cycles.
Molecular Weight	Observed: 281kDa
Manufacturer - Research Area	Cell Cycle, Signal Transduction
Background	The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene.
Purification	Affinity purification
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH 7.3
Immunogen	Recombinant protein of human FLNA
Clonality	Monoclonal
NCBI Official Name	filamin A, alpha
NCBI Organism	Homo sapiens
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 50 uL

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Lieferung vsl. bis 04.09.2025

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