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PRKAA1 Antibody

ArtNr PRS-13-948-50uL
Hersteller ProSci
Menge 50 uL
Kategorie
Typ Antibody Primary
Format Liquid
Applikationen WB
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
Isotype IgG
Konjugat/Tag Unconjugated
NCBI PRKAA1
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias PRKAA1, AMPK, AMPKa1, MGC33776, MGC57364
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Manufacturer - Applications
WB: 1:500 - 1:2000
Shipping Temperature
blue ice or room temperature
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Molecular Weight
Observed: 62kDa
Manufacturer - Research Area
Apoptosis, Autophagy, Cancer, Cell Cycle, Neuroscience, Signal Transduction
Background
The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
Purification
Affinity purification
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH 7.3
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human PRKAA1 (NP_006242.5).
Clonality
Polyclonal
NCBI Official Name
protein kinase, AMP-activated, alpha 1 catalytic subunit
NCBI Organism
Homo sapiens
Disclaimer
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 50 uL
Lieferbar: In stock
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