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CCRL2 Antibody

ArtNr PRS-25-176-100ul
Hersteller ProSci
Menge 100 ul
Kategorie
Typ Antibody Polyclonal
Format Liquid
Applikationen WB, ELISA
Specific against Human (Homo sapiens)
Host Rabbit
Konjugat/Tag Unconjugated
Citations Galligan, C.L., (2004) Arthritis Rheum. 50 (6), 1806-1814.
NCBI CCRL2
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias CCRL2,CKRX,CRAM-A,CRAM-B,HCR,MGC116710,CRAM,ACKR5,CCRL2
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Type
Primary Antibodies
Shipping Temperature
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store CCRL2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Molecular Weight
39 kDa
Manufacturer - Research Area
Membrane , Signal Transduction , Immunology
Background
CCRL2 is a chemokine receptor like protein, which is predicted to be a seven transmembrane protein and most closely related to CCR1. Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. CCRL2 gene is expressed at high levels in primary neutrophils and primary monocytes, and is further upregulated on neutrophil activation and during monocyte to macrophage differentiation. The function of this gene is unknown. This gene is mapped to the region where the chemokine receptor gene cluster is located.This gene encodes a chemokine receptor like protein, which is predicted to be a seven transmembrane protein and most closely related to CCR1. Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. This gene is expressed at high levels in primary neutrophils and primary monocytes, and is further upregulated on neutrophil activation and during monocyte to macrophage differentiation. The function of this gene is unknown. This gene is mapped to the region where the chemokine receptor gene cluster is located.
By Type
Membrane, Signal Transduction, Immunology
Modifications
None
Protein Gi #
68215224
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control 1
721_B Cell Lysate
Concentration
batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Application Note
CCRL2 antibody can be used for detection of CCRL2 by ELISA at 1:1562500. CCRL2 antibody can be used for detection of CCRL2 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50, 000 - 100, 000.
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CCRL2.
Clonality
Polyclonal
NCBI Official Name
chemokine (C-C motif) receptor-like 2
NCBI Organism
Homo sapiens
Disclaimer
This product is for research use only.
User Note
Optimal dilutions for each application to be determined by the researcher.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ul
Lieferbar: In stock
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