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COPS2 Antibody

ArtNr PRS-28-869-100ul
Hersteller ProSci
Menge 100 ul
Kategorie
Typ Antibody Polyclonal
Format Liquid
Applikationen WB, IHC, ELISA
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus), Dog (Canine, Canis lupus familiaris), Zebrafish (Danio rerio)
Host Rabbit
Konjugat/Tag Unconjugated
Citations Moehren, U., (2004) (er) Nucleic Acids Res. 32 (10), 2995-3004.
NCBI COPS2
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias COPS2,ALIEN,CSN2,SGN2,TRIP15
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Type
Primary Antibodies
Shipping Temperature
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store COPS2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Molecular Weight
51 kDa
Manufacturer - Research Area
Transcription , Cancer , Signal Transduction
Background
COPS2 is an essential component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP. COPS2 is also innvolved in early stage of neuronal differentiation via its interaction with NIF3L1.
By Type
Transcription, Cancer, Signal Transduction
Modifications
None
Protein Gi #
4759264
Purification
Antibody is purified by protein A chromatography method.
Positive Control 1
Tranfected 293T Cell Lysate
Concentration
batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Application Note
COPS2 antibody can be used for detection of COPS2 by ELISA at 1:312500. COPS2 antibody can be used for detection of COPS2 by western blot at 2.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50, 000 - 100, 000.
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human COPS2.
Clonality
Polyclonal
NCBI Official Name
COP9 signalosome subunit 2
NCBI Organism
Homo sapiens
Disclaimer
This product is for research use only.
User Note
Optimal dilutions for each application to be determined by the researcher.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ul
Lieferbar: In stock
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