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PRKAA1 Antibody

ArtNr PRS-30-953-100ul
Hersteller ProSci
Menge 100 ul
Kategorie
Typ Antibody Polyclonal
Format Liquid
Applikationen WB, ELISA
Specific against Human (Homo sapiens)
Host Rabbit
Konjugat/Tag Unconjugated
Citations Hasumi, H., Gene 415 (1-2), 60-67 (2008).
NCBI PRKAA1
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias PRKAA1,AMPK,AMPKa1,MGC33776,MGC57364
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Type
Primary Antibodies
Shipping Temperature
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store PRKAA1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Molecular Weight
62 kDa
Manufacturer - Research Area
Cancer , Signal Transduction , Immunology , Apoptosis
Background
PRKAA1 belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways.The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
By Type
Cancer, Signal Transduction, Immunology, Apoptosis
Modifications
None
Protein Gi #
94557299
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control 1
Cat. No. XBL-10413 - Fetal Skeletal Muscle Tissue Lysate
Concentration
batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Application Note
PRKAA1 antibody can be used for detection of PRKAA1 by ELISA at 1:62500. PRKAA1 antibody can be used for detection of PRKAA1 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50, 000 - 100, 000.
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PRKAA1.
Clonality
Polyclonal
NCBI Official Name
protein kinase, AMP-activated, alpha 1 catalytic subunit
NCBI Organism
Homo sapiens
Disclaimer
This product is for research use only.
User Note
Optimal dilutions for each application to be determined by the researcher.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ul
Lieferbar: In stock
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