NR2F2 Antibody

blue ice or room temperature

45 kDa

NR2F2, an orphan member of the nuclear hormone receptor superfamily, acts as a transcriptional repressor by antagonizing the functions of other nuclear hormone receptors and by actively silencing transcription. However, in certain contexts, NR2F2 stimulates transcription directly. NR2F2, MyoD and p300 interact in a competitive manner, and that increasing amounts of NR2F2 have the ability to reduce the interaction between myoD and p300 invitro. NR2F2 post-transcriptionally regulates myoD activity/function, and that crosstalk between orphan nuclear receptors and the myogenic bHLH proteins has functional consequences for differentiation.

Antibody is purified by peptide affinity chromatography method.

Batch dependent

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NR2F2.

nuclear receptor subfamily 2, group F, member 2

This product is for research use only.