Hersteller |
ProSci
|
Kategorie |
|
Typ |
Antibody Polyclonal |
Specific against |
Human, Mouse, Rat |
Format |
Liquid |
Applikationen |
WB, ELISA |
Menge |
100 ul |
Host |
Rabbit |
ArtNr |
PRS-31-255-100ul |
eClass 6.1 |
32160702 |
eClass 9.0 |
32160702 |
Lieferbar |
|
Shipping |
blue ice or RT |
By Research Area |
Transcription |
Immunogen |
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SOX2. |
Applications |
SOX2 antibody can be used for detection of SOX2 by ELISA at 1:12500. SOX2 antibody can be used for detection of SOX2 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50, 000 - 100, 000. |
Positive Control 1 |
OVCAR-3 Cell Lysate |
Predicted Molecular Weight |
34 kDa |
Purification |
Antibody is purified by peptide affinity chromatography method. |
Clonality |
Polyclonal |
Conjugate |
Unconjugated |
Buffer |
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Concentration |
batch dependent |
Storage Conditions |
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store SOX2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles. |
Disclaimer |
This product is for research use only. |
Modifications |
None |
Ncbi Official Symbol |
SOX2 |
Accession # |
NP_003097 |
Protein Gi # |
28195386 |
Ncbi Gene Id # |
6657 |
User Note |
Optimal dilutions for each application to be determined by the researcher. |
Ncbi Official Symbol |
SOX2 |
Ncbi Official Full Name |
SRY (sex determining region Y)-box 2 |
Ncbi Organism |
Homo sapiens |
Swissprot # |
P48431 |
Background |
SOX2 is a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The protein may act as a transcriptional activator after forming a protein complex with other proteins. Mutations in this gene have been associated with bilateral anophthalmia, a severe form of structural eye malformation. This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
Background References 1 |
Wang, P., (2008) Arch. Ophthalmol. 126 (5), 709-713 . |
1st Image Caption |
Antibody used in IHC. |
2nd Image Caption |
Antibody used in WB on Human OVCAR-3 at 0.2-1 ug/ml. |
3rd Image Caption |
Antibody used in IHC on Human Spleen. |
4th Image Caption |
Antibody used in IHC on Human Kidney. |
5th Image Caption |
Antibody used in WB on U87 at 1:1000. |
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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.