Desmin Antibody [10H7D2]

Blue Ice

Desmin (DES), with 470-amino acid protein (about 52 kDa), belongs to the intermediate filament family and Desmin is class III intermediate filaments found in muscle cells. Homopolymers of Desmin form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane.Mutations in Desmin are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies.Desmin is also expressed in smooth muscle cells of both airways and alveolar ducts and Desmin is a load-bearing protein that stiffens the airways and consequently the lung and modulates airway contractile response.

None

batch dependent

Western Blot:1:1, 000 - 1:2, 000
IHC(P):1:1, 000 - 1:2, 000
IHC(F):1:1, 000 - 1:2, 000
ELISA:Propose dilution 1:10, 000.
Determining optimal working dilutions by titration test.

Monoclonal

Homo sapiens

Optimal dilutions for each application to be determined by the researcher.