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CD11c Antibody [HC1/1]

ArtNr PRS-33-158-100ug
Hersteller ProSci
Menge 100 ug
Kategorie
Typ Antibody Monoclonal
Format Liquid
Applikationen FC, IF, Blocking
Clon HC1/1
Specific against Human (Homo sapiens)
Host Mouse
Isotype IgG1 Kappa
Konjugat/Tag Unconjugated
NCBI ITGAX
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias Integrin alpha-X,CD11 antigen-like family member C,Leu M5,Leukocyte adhesion glycoprotein p150,95 alpha chain,Leukocyte adhesion receptor p150,CD11c,ITGAX,CD11C
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Type
Primary Antibodies
Shipping Temperature
Blue Ice
Storage Conditions
Aliquot and Store at 2-8˚ C. Avoid freez-thaw cycles.
Manufacturer - Research Area
Immunology, Signal Transduction
Background
CD11c, also known as Integrin alpha X (complement component 3 receptor 4 subunit) (ITGAX), is a type I transmembrane protein found at high levels on most human dendritic cells, but also on monocytes, macrophages, neutrophils, and some B cells that induces cellular activation and helps trigger neutrophil respiratory burst; expressed in hairy cell leukemias, acute non-lymphocytic leukemias, and some B-cell chronic lymphocytic leukemias.
By Type
Immunology, Signal Transduction
Modifications
None
Purification
Protein G affinity chromatography
Concentration
0.2 mg/mL
Buffer
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Application Note
Flow Cytometry: 0.5-1 ug/million cells
IF: 0.5-1 ug/ml
Functional Activity (Blocking): order BSA/azide free format

The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the CD11c antibody to be titered up or down for optimal performance.
Immunogen
Human monocytic U937 phorbol ester-treated cells were used as the immunogen for this CD11c antibody.
Clonality
Monoclonal
NCBI Official Name
integrin, alpha X (complement component 3 receptor 4 subunit)
NCBI Organism
Homo sapiens
Disclaimer
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
User Note
Optimal dilutions for each application to be determined by the researcher

Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.

Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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