AMACR / p504S Antibody [AMACR/1723]

Primary Antibodies

Aliquot and Store at 2-8˚ C. Avoid freez-thaw cycles.

AMACR, also known as p504S is an enzyme that is involved in bile acid biosynthesis and beta-oxidation of branched-chain fatty acids. It is expressed in cells of premalignant high-grade prostatic intraepithelial neoplasia (HGPIN) and prostate adenocarcinoma. The majority of the carcinoma cells show a distinct granular cytoplasmic staining reaction. AMACR is present at low or undetectable levels in glandular epithelial cells of normal prostate and benign prostatic hyperplasia. A spotty granular cytoplasmic staining is seen in a few cells of the benign glands.

None

0.2 mg/mL

Immunohistology (FFPE): 1-2 ug/ml for 30 minutes at RT
IF: 1-2 ug/ml
Optimal dilution of the AMACR antibody should be determined by the researcher.

Monoclonal

Homo sapiens

Optimal dilutions for each application to be determined by the researcher