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CFTR Antibody [CFTR/1643]

CFTR Antibody [CFTR/1643]

ArtNr	PRS-33-777-100ug
Hersteller	ProSci
Menge	100 ug
Kategorie	Oncology Antibodies By Cell Type Carcinoma Immunohistochemistry Immunofluorescence Primary Antibodies By Organ Testicular & Prostate Cancer Renal Cancer
Typ	Antibody Monoclonal
Format	Liquid
Applikationen	IF, IHC-P
Clon	CFTR/1643
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG2b
Konjugat/Tag	Unconjugated
NCBI	CFTR
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	CFTR Antibody: CF, MRP7, ABC35, ABCC7, CFTR/MRP, TNR-CFTR, dJ760C5.1, Cystic fibrosis transmembrane conductance regulator, ATP-binding cassette sub-family C member 7, CFTR
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Manufacturer - Applications	IF: 0.5-1 ug/ml IHC (FFPE): 1-2 ug/ml for 30 min at RT The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the CFTR antibody to be titered up or down for optimal performance.
Shipping Temperature	blue ice or room temperature
Storage Conditions	Aliquot and Store at 2-8°C. Avoid freez-thaw cycles.
Manufacturer - Research Area	Signal Transduction
Background	Cystic fibrosis transmembrane conductance regulator (CFTR) is involved in the transport of chloride ions. May regulate bicarbonate secretion and salvage in epithelial cells by regulating the SLC4A7 transporter. Can inhibit the chloride channel activity of ANO1. Plays a role in the chloride and bicarbonate homeostasis during sperm epididymal maturation and capacitation. [UniProt]
Purification	Protein G affinity chromatography
Concentration	0.2 mg/mL
Buffer	PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Immunogen	A partial recombinant protein corresponding to amino acids 258-385 from the human protein was used as the immunogen for this CFTR antibody.
Clonality	Monoclonal
NCBI Official Name	cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
NCBI Organism	homo sapiens
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 100 ug

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Lieferung vsl. bis 02.10.2025

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