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PD-1 Antibody [PD203-1]

ArtNr PRS-33-860-100ug
Hersteller ProSci
Menge 100 ug
Kategorie
Typ Antibody Monoclonal
Format Liquid
Applikationen FC, IF, IHC-P
Clon PD203-1
Specific against Human (Homo sapiens)
Host Mouse
Isotype IgG1 Kappa
Konjugat/Tag Unconjugated
NCBI PDCD1
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias PD-1 Antibody: PD1,PD-1,CD279,SLEB2,hPD-1,hPD-l,hSLE1,PD1,Programmed cell death protein 1,Protein PD-1,PDCD1,PDCD-1
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Type
Primary Antibodies
Shipping Temperature
Blue Ice
Storage Conditions
Aliquot and Store at 2-8˚ C. Avoid freez-thaw cycles.
Manufacturer - Research Area
Immunology, Cancer, Cell Cycle
Background
Programmed cell death protein 1 is an inhibitory cell surface receptor involved in the regulation of T-cell function during immunity and tolerance. Upon ligand binding, inhibits T-cell effector functions in an antigen-specific manner. Possible cell death inducer, in association with other factors. [UniProt]
By Type
Immunology, Cancer, Cell Cycle
Modifications
None
Purification
Protein G affinity chromatography
Concentration
0.2 mg/mL
Buffer
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Application Note
Immunohistochemistry (FFPE): 0.5-1 ug/ml for 30 min at RT (1)
Prediluted format: incubate for 30 min at RT (2)
Immunofluorescence: 1-2 ug/ml
Flow Cytometry: 0.5-1 ug/million cells in 0.1ml
Titering of the anti-PD-1 antibody may be required for optimal performance.

1. FFPE testing requires tissue to be boiled in 10mM Tris with 1mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 min
2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Immunogen
Recombinant full-length human protein was used as the immunogen for the anti-PD-1 antibody.
Clonality
Monoclonal
NCBI Official Name
programmed cell death 1
NCBI Organism
mus musculus
Disclaimer
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
User Note
Optimal dilutions for each application to be determined by the researcher

Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.

Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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