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Bax Antibody [SPM336]

Bax Antibody [SPM336]

ArtNr	PRS-34-157-100ug
Hersteller	ProSci
Menge	100 ug
Kategorie	Oncology Neuroscience Neural Lineage Markers Molecular Targets for Neuroscience Neural Development Antibodies Cell Biology Cell Status Apoptosis Flow Cytometry Immunohistochemistry Western Blot Immunofluorescence Primary Antibodies By Organ Lung Cancer Thyroid Cancer
Typ	Antibody Monoclonal
Format	Liquid
Applikationen	WB, FC, IF, IHC
Clon	SPM336
Specific against	Human (Homo sapiens), Monkey (Cynomolgus, Simian)
Host	Mouse
Isotype	IgG1
Konjugat/Tag	Unconjugated
NCBI	BAX
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Bax Antibody: BCL2L4,BCL2L4,Apoptosis regulator BAX,Bcl-2-like protein 4,Bcl2-L-4
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Primary Antibodies
Shipping Temperature	Blue Ice
Storage Conditions	Aliquot and Store at 2-8˚ C. Avoid freez-thaw cycles.
Manufacturer - Research Area	Apoptosis, Autophagy, Cancer
Background	Recognizes a protein of 21kDa, identified as the Bax protein. This mAb is highly specific to Bax and shows no cross-reaction with Bcl-2 or Bcl-X protein. Bcl-2 blocks cell death following a variety of stimuli. Bax has extensive amino acid homology with Bcl-2 and it homodimerizes and forms heterodimers with Bcl-2. Overexpression of Bax accelerates apoptotic death induced by cytokine deprivation in an IL-3 dependent cell line, and Bax also counters the death repressor activity of Bcl-2.
By Type	Apoptosis, Autophagy, Cancer
Modifications	None
Purification	Protein G affinity chromatography
Concentration	0.2 mg/mL
Buffer	PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Application Note	Flow Cytometry: 0.5-1 ug/million cells in 0.1ml Immunofluorescence: 1-2 ug/ml Western blot: 0.5-1 ug/ml Immunohistochemistry (FFPE): 0.5-1 ug/ml for 30 minutes at RT (1) Prediluted format : incubate for 30 min at RT (2) The optimal dilution of the anti-Bax antibody for each application should be determined by the researcher. 1. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes. 2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.
Manufacturer - Specificity	Does not react with mouse and rat
Immunogen	Amino acids 3-16 (GSGEQPRGGGPTSS) from the human protein were used as the immunogen for this anti-Bax antibody.
Clonality	Monoclonal
NCBI Official Name	BCL2-associated X protein
NCBI Organism	Homo sapiens
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
User Note	Optimal dilutions for each application to be determined by the researcher

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 100 ug

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Lieferung vsl. bis 06.11.2025

Express-Lieferung: 1 Tage sparen

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