TRAIL-R2 Antibody [HS201] (biotin)

ArtNr	PRS-36-130-100ug
Hersteller	ProSci
Menge	100 ug
Kategorie	Oncology Antibodies By Cell Type Carcinoma Hematology Myeloma Cell Biology Cell Status Apoptosis Flow Cytometry Immunohistochemistry Immunoprecipitation Immunocytochemistry Primary Antibodies
Typ	Antibody Primary
Format	Liquid
Applikationen	FC, IP, IHC, ICC, FA
Clon	HS201
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1
Konjugat/Tag	Biotin
NCBI	TNFRSF10B
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	TRAIL Receptor 2,DR5,KILLER,TNFRSF10B,CD262
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Primary Antibodies, Functional Antibodies
Shipping Temperature	Blue Ice
Storage Conditions	Stable for at least 1 year after receipt when stored at -20˚ C.
Manufacturer - Research Area	Apoptosis, Cancer, Immunology, Functional Assays
Background	TRAIL-R2 is a receptor for the cytotoxic ligand TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappaB.
By Type	Apoptosis, Cancer, Immunology
Modifications	None
Protein Gi #	AF012535
Purification	>95% (SDS-PAGE)
Concentration	0.5 mg/ml
Buffer	Liquid. In PBS containing 0.02% sodium azide.
Application Note	Functional Application: Inhibition (blocks TRAIL-R2 mediated killing if applied in solution). Immunohistochemistry: (paraffin sections, 15ug/ml).
Manufacturer - Specificity	Recognizes human TRAIL-R2. Does not cross-react with human TRAIL-R1, -R3 or -R4.
Immunogen	Recombinant human TRAIL-R2 (DR5).
Clonality	Monoclonal
NCBI Official Name	tumor necrosis factor receptor superfamily, member 10b
NCBI Organism	Homo sapiens
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
User Note	Optimal dilutions for each application to be determined by the researcher.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 100 ug

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Lieferung vsl. bis 01.01.2026

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