Bmf Antibody [9G10]

Primary Antibodies

Stable for at least 1 year after receipt when stored at -20˚ C.

Bmf (Bcl-2-modifying factor) belongs to the Bcl-2 protein family. Bcl-2 family members form hetero- or homo-dimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. Bmf contains a single Bcl-2 homology domain 3 (BH3), and has been shown to interact with other Bcl-2 proteins and functions as an apoptotic activator. Two different start sites can give rise to two proteins of 25 or 30 kDa. It is found to be sequestered to myosin V motors by its association with dynein light chain 2 (DLC2), which may be important for sensing intracellular damage and triggering apoptosis.

None

>95% (SDS-PAGE)

Liquid. In PBS containing 0.02% sodium azide.

Recognizes human and mouse Bmf. Detects several cross-reactivity bands of unknown identity in mice by western blot.

Monoclonal

Homo sapiens

Optimal dilutions for each application to be determined by the researcher.