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COL18A1 Antibody

ArtNr PRS-55-358-400ul
Hersteller ProSci
Menge 400 ul
Kategorie
Typ Antibody Polyclonal
Format Liquid
Applikationen WB, IHC-P
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host Rabbit
Konjugat/Tag Unconjugated
Citations Hamano, Y., et al. J. Am. Soc. Nephrol. 21(9):1445-1455(2010)
Roberts, K.E., et al. Gastroenterology 139(1):130-139(2010)
Lee, K.S., et al. Tumour Biol. 31(3):165-170(2010)
Faye, C., et al. Biochem. J. 427(3):467-475(2010)
NCBI COL18A1
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Collagen alpha-1(XVIII) chain,Endostatin,COL18A1
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Type
Primary Antibodies
Manufacturer - Isotype
Rabbit Ig
Shipping Temperature
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Molecular Weight
178 kDa
Manufacturer - Research Area
Cancer, Signal Transduction
Background
COL18A1 is the alpha chain of type XVIII collagen.
This collagen is one of the multiplexins, extracellular matrix
proteins that contain multiple triple-helix domains (collagenous
domains) interrupted by non-collagenous domains. The
proteolytically produced C-terminal fragment of type XVIII collagen
is endostatin, a potent antiangiogenic protein. Mutations in this
gene are associated with Knobloch syndrome. The main features of
this syndrome involve retinal abnormalities, so type XVIII collagen
may play an important role in retinal structure and in neural tube
closure.
By Type
Cancer, Signal Transduction
Modifications
None
Protein Gi #
215274264
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Application Note
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100
Immunogen
This COL18A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1311-1339 amino acids from the Central region of human COL18A1.
Clonality
Polyclonal
NCBI Official Name
Collagen alpha-1(XVIII) chain
NCBI Organism
Homo sapiens
Disclaimer
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
User Note
Optimal dilutions for each application to be determined by the researcher.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 400 ul
Lieferbar: In stock
lieferbar

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