PCDHB10 Antibody

Primary Antibodies

Blue Ice

88 kDa

This gene is a member of the protocadherin beta gene
cluster, one of three related gene clusters tandemly linked on
chromosome five. The gene clusters demonstrate an unusual genomic
organization similar to that of B-cell and T-cell receptor gene
clusters. The beta cluster contains 16 genes and 3 pseudogenes,
each encoding 6 extracellular cadherin domains and a cytoplasmic
tail that deviates from others in the cadherin superfamily. The
extracellular domains interact in a homophilic manner to specify
differential cell-cell connections. Unlike the alpha and gamma
clusters, the transcripts from these genes are made up of only one
large exon, not sharing common 3' exons as expected. These neural
cadherin-like cell adhesion proteins are integral plasma membrane
proteins. Their specific functions are unknown but they most likely
play a critical role in the establishment and function of specific
cell-cell neural connections.

None

This antibody is purified through a protein A column, followed by peptide affinity purification.

Supplied in PBS with 0.09% (W/V) sodium azide.

This PCDHB10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 766-794 amino acids from the C-terminal region of human PCDHB10.

Protocadherin beta-10

Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.