CLCN7 Antibody

Primary Antibodies

Blue Ice

89 kDa

The product of this gene belongs to the CLC chloride
channel family of proteins. Chloride channels play important roles
in the plasma membrane and in intracellular organelles. This gene
encodes chloride channel 7. Defects in this gene are the cause of
osteopetrosis autosomal recessive type 4 (OPTB4), also called
infantile malignant osteopetrosis type 2 as well as the cause of
autosomal dominant osteopetrosis type 2 (OPTA2), also called
autosomal dominant Albers-Schonberg disease or marble disease
autosoml dominant. Osteopetrosis is a rare genetic disease
characterized by abnormally dense bone, due to defective resorption
of immature bone. OPTA2 is the most common form of osteopetrosis,
occurring in adolescence or adulthood.

None

This antibody is purified through a protein A column, followed by peptide affinity purification.

Supplied in PBS with 0.09% (W/V) sodium azide.

Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat

Polyclonal

Homo sapiens

Optimal dilutions for each application to be determined by the researcher.