IRF9 Antibody

ArtNr	PRS-56-092-400ul
Hersteller	ProSci
Menge	400 ul
Kategorie	Oncology Neuroscience Neuroinflammation Antibodies By Cell Type Carcinoma Glioma Cell Biology Cell Culture Cytokines Mesothelioma Immunohistochemistry Western Blot Immunofluorescence Primary Antibodies By Organ Colorectal Cancer
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB, IF, IHC-P
Specific against	Mouse (Murine, Mus musculus)
Host	Rabbit
Konjugat/Tag	Unconjugated
Citations	Maiwald, T., et al. FEBS J. 277(22):4741-4754(2010) Schuurhof, A., et al. Pediatr. Pulmonol. 45(6):608-613(2010) Watanabe, T., et al. J. Clin. Invest. 120(5):1645-1662(2010) Mosbruger, T.L., et al. J. Infect. Dis. 201(9):1371-1380(2010)
NCBI	IRF9
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Interferon regulatory factor 9, IRF-9, IFN-alpha-responsive transcription factor subunit, ISGF3 p48 subunit, Interferon-stimulated gene factor 3 gamma, ISGF-3 gamma, Transcriptional regulator ISGF3 subunit gamma, IRF9, ISGF3G
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Manufacturer - Applications	For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:10~50 For IF starting dilution is: 1:10~50
Manufacturer - Isotype	Rabbit Ig
Shipping Temperature	blue ice or room temperature
Storage Conditions	Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Molecular Weight	44 kDa
Manufacturer - Research Area	Immunology
Background	IRF9 is a transcription regulatory factor that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with IRF9/ISGF3G to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.
Protein Gi #	266392
Purification	This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration	Batch dependent
Buffer	Supplied in PBS with 0.09% (W/V) sodium azide.
Immunogen	This IRF9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 75-104 amino acids from the N-terminal region of human IRF9.
Clonality	Polyclonal
NCBI Official Name	Interferon regulatory factor 9
NCBI Organism	Homo sapiens
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 400 ul

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Lieferung vsl. bis 04.09.2025

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