ARRB1 Antibody

Primary Antibodies

Blue Ice

47 kDa

Members of arrestin/beta-arrestin protein family are
thought to participate in agonist-mediated desensitization of
G-protein-coupled receptors and cause specific dampening of
cellular responses to stimuli such as hormones, neurotransmitters,
or sensory signals. Arrestin beta 1 is a cytosolic protein and
acts as a cofactor in the beta-adrenergic receptor kinase (BARK)
mediated desensitization of beta-adrenergic receptors. Besides the
central nervous system, it is expressed at high levels in
peripheral blood leukocytes, and thus the BARK/beta-arrestin system
is believed to play a major role in regulating receptor-mediated
immune functions. Alternatively spliced transcripts encoding
different isoforms of arrestin beta 1 have been described, however,
their exact functions are not known.

None

This antibody is purified through a protein A column, followed by peptide affinity purification.

Supplied in PBS with 0.09% (W/V) sodium azide.

Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rabbit, Rat

Polyclonal

Homo sapiens

Optimal dilutions for each application to be determined by the researcher.