HIST3H3 Antibody

Rabbit Ig

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Histones are basic nuclear proteins that are responsible
for the nucleosome structure of the chromosomal fiber in
eukaryotes. Nucleosomes consist of approximately 146 bp of DNA
wrapped around a histone octamer composed of pairs of each of the
four core histones (H2A, H2B, H3, and H4). The chromatin fiber is
further compacted through the interaction of a linker histone, H1,
with the DNA between the nucleosomes to form higher order chromatin
structures. This gene is intronless and encodes a member of the
histone H3 family. Transcripts from this gene lack polyA tails;
instead, they contain a palindromic termination element. This gene
is located separately from the other H3 genes that are in the
histone gene cluster on chromosome 6p22-p21.3. [provided by
RefSeq].

None

This antibody is purified through a protein A column, followed by peptide affinity purification.

Supplied in PBS with 0.09% (W/V) sodium azide.

This HIST3H3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 50-78 amino acids from the Central region of human HIST3H3.

Histone H3.1t

Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.