ATF4 Antibody

Rabbit Ig

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

This gene encodes a transcription factor that was
originally identified as a widely expressed mammalian DNA binding
protein that could bind a tax-responsive enhancer element in the
LTR of HTLV-1. The encoded protein was also isolated and
characterized as the cAMP-response element binding protein 2
(CREB-2). The protein encoded by this gene belongs to a family of
DNA-binding proteins that includes the AP-1 family of transcription
factors, cAMP-response element binding proteins (CREBs) and
CREB-like proteins. These transcription factors share a leucine
zipper region that is involved in protein-protein interactions,
located C-terminal to a stretch of basic amino acids that functions
as a DNA binding domain. Two alternative transcripts encoding the
same protein have been described. Two pseudogenes are located on
the X chromsome at q28 in a region containing a large inverted
duplication.

None

This antibody is purified through a protein A column, followed by peptide affinity purification.

Supplied in PBS with 0.09% (W/V) sodium azide.

This ATF4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 171-198 amino acids from the Central region of human ATF4.

Cyclic AMP-dependent transcription factor ATF-4

Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

Cyclic AMP-dependent transcription factor ATF-4, cAMP-dependent transcription factor ATF-4, Activating transcription factor 4, Cyclic AMP-responsive element-binding protein 2, CREB-2, cAMP-responsive element-binding protein 2, DNA-binding protein TAXREB67, Tax-responsive enhancer element-binding protein 67, TaxREB67, ATF4, CREB2, TXREB