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AKR1C2 Antibody

ArtNr PRS-56-299-400ul
Hersteller ProSci
Menge 400 ul
Kategorie
Typ Antibody Polyclonal
Format Liquid
Applikationen WB, IHC-P
Specific against Human (Homo sapiens)
Host Rabbit
Konjugat/Tag Unconjugated
Citations Setlur, S.R., et al. Cancer Epidemiol. Biomarkers Prev. 19(1):229-239(2010)
Wang, X., et al. PLoS ONE(8), E11934 (2010) :
Reding, K.W., et al. Am. J. Epidemiol. 170(10):1241-1249(2009)
Cogliati, C., et al. FEBS J. 276(20):6011-6023(2009)
NCBI AKR1C2
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Aldo-keto reductase family 1 member C2, 1---, 3-alpha-HSD3, Chlordecone reductase homolog HAKRD, Dihydrodiol dehydrogenase 2, DD-2, DD2, Dihydrodiol dehydrogenase/bile acid-binding protein, DD/BABP, Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase, Type II
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Type
Primary Antibodies
Manufacturer - Isotype
Rabbit Ig
Shipping Temperature
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Molecular Weight
37 kDa
Manufacturer - Research Area
Cancer, Cell Cycle, Obesity, Signal Transduction
Background
This gene encodes a member of the aldo/keto reductase
superfamily, which consists of more than 40 known enzymes and
proteins. These enzymes catalyze the conversion of aldehydes and
ketones to their corresponding alcohols using NADH and/or NADPH as
cofactors. The enzymes display overlapping but distinct substrate
specificity. This enzyme binds bile acid with high affinity, and
shows minimal 3-alpha-hydroxysteroid dehydrogenase activity. This
gene shares high sequence identity with three other gene members
and is clustered with those three genes at chromosome 10p15-p14.
By Type
Cancer, Cell Cycle, Obesity, Signal Transduction
Modifications
None
Protein Gi #
20532374
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Application Note
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
Homology
Predicted species reactivity based on immunogen sequence: Monkey
Immunogen
This AKR1C2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 296-323 amino acids from the C-terminal region of human AKR1C2.
Clonality
Polyclonal
NCBI Official Name
Aldo-keto reductase family 1 member C2
NCBI Organism
Homo sapiens
Disclaimer
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
User Note
Optimal dilutions for each application to be determined by the researcher.
Manufacturer - Additional Names
Aldo-keto reductase family 1 member C2, 1---, 3-alpha-HSD3, Chlordecone reductase homolog HAKRD, Dihydrodiol dehydrogenase 2, DD-2, DD2, Dihydrodiol dehydrogenase/bile acid-binding protein, DD/BABP, Trans-1, 2-dihydrobenzene-1, 2-diol dehydrogenase, Type III 3-alpha-hydroxysteroid dehydrogenase, AKR1C2, DDH2

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 400 ul
Lieferbar: In stock
lieferbar

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