ARHB Antibody

ArtNr	PRS-56-309-400ul
Hersteller	ProSci
Menge	400 ul
Kategorie	Antibodies Cell Biology Cytoskeleton Immunohistochemistry Western Blot Primary Antibodies small GTPases Rho Subfamily
Typ	Antibody
Format	Liquid
Applikationen	WB, IHC-P
Specific against	Human (Homo sapiens)
Host	Rabbit
Konjugat/Tag	Unconjugated
Citations	Adly, M.A., et al. J. Cutan. Pathol. 37(7):751-757(2010) Connolly, E.C., et al. Mol. Cancer Res. 8(5):691-700(2010) Zintzaras, E., et al. Am. J. Epidemiol. 171(8):851-858(2010) Kim, C.H., et al. Biochem. Biophys. Res. Commun. 391(2):1182-1186(2010)
NCBI	RHOB
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Rho-related GTP-binding protein RhoB,Rho cDNA clone 6,h6,RHOB,ARH6,ARHB
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Primary Antibodies
Manufacturer - Isotype	Rabbit Ig
Shipping Temperature	Blue Ice
Storage Conditions	Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Molecular Weight	22 kDa
Manufacturer - Research Area	Cancer, Signal Transduction
Background	ARHB mediates apoptosis in neoplastically transformed cells after DNA damage. Not essential for development but affects cell adhesion and growth factor signaling in transformed cells. Plays a negative role in tumorigenesis as deletion causes tumor formation. Involved in intracellular protein trafficking of a number of proteins. Targets PKN1 to endosomes and is involved in trafficking of the EGF receptor from late endosomes to lysosomes. Also required for stability and nuclear trafficking of AKT1/AKT which promotes endothelial cell survival during vascular development.
By Type	Cancer, Signal Transduction
Modifications	None
Protein Gi #	51338601
Purification	This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration	batch dependent
Buffer	Supplied in PBS with 0.09% (W/V) sodium azide.
Application Note	For WB starting dilution is: 1:4000 For IHC-P starting dilution is: 1:10~50
Homology	Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat
Immunogen	This ARHB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 104-137 amino acids from the Central region of human ARHB.
Clonality	Polyclonal
NCBI Official Name	Rho-related GTP-binding protein RhoB
NCBI Organism	Homo sapiens
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
User Note	Optimal dilutions for each application to be determined by the researcher.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 400 ul

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