TGFB1 Antibody

ArtNr	PRS-56-364-400ul
Hersteller	ProSci
Menge	400 ul
Kategorie	Oncology Antibodies Immunohistochemistry Western Blot Immunofluorescence Primary Antibodies By Organ Colorectal Cancer
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB, IF, IHC-P
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Konjugat/Tag	Unconjugated
Citations	Perez, A.B., et al. Hum. Immunol. 71(11):1135-1140(2010) Xu, Z., et al. Biochem. Biophys. Res. Commun. 401(3):376-381(2010) Bran, G.M., et al. Anticancer Res. 30(9):3459-3463(2010) Zauli, G., et al. Blood 80(12):3036-3043(1992) Wrana, J.L., et al. Cell 71(6):1003-1014(1992)
NCBI	TGFB1
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Transforming growth factor beta-1,TGF-beta-1,Latency-associated peptide,LAP,TGFB1,TGFB
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Primary Antibodies
Manufacturer - Isotype	Rabbit Ig
Shipping Temperature	Blue Ice
Storage Conditions	Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Molecular Weight	44 kDa
Manufacturer - Research Area	Cancer, Cell Cycle, Obesity, Signal Transduction
Background	TGFB1 is a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types. Many cells have TGFB receptors, and the protein positively and negatively regulates many other growth factors. The secreted protein is cleaved into a latency-associated peptide (LAP) and a mature TGFB1 peptide, and is found in either a latent form composed of a TGFB1 homodimer, a LAP homodimer, and a latent TGFB1-binding protein, or in an active form composed of a TGFB1 homodimer. The mature peptide may also form heterodimers with other TGFB family members. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease.
By Type	Cancer, Cell Cycle, Obesity, Signal Transduction
Modifications	None
Protein Gi #	135674
Purification	This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration	batch dependent
Buffer	Supplied in PBS with 0.09% (W/V) sodium azide.
Application Note	For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:10~50 For IF starting dilution is: 1:10~50
Homology	Predicted species reactivity based on immunogen sequence: Rat, Pig, Bovine
Immunogen	This TGFB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 22-50 amino acids from the N-terminal region of human TGFB1.
Clonality	Polyclonal
NCBI Official Name	Transforming growth factor beta-1
NCBI Organism	Homo sapiens
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
User Note	Optimal dilutions for each application to be determined by the researcher.

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Menge: 400 ul

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Lieferung vsl. bis 06.11.2025

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