PSMB10 Antibody

Primary Antibodies

Blue Ice

29 kDa

The proteasome is a multicatalytic proteinase complex with
a highly ordered ring-shaped 20S core structure. The core structure
is composed of 4 rings of 28 non-identical subunits; 2 rings are
composed of 7 alpha subunits and 2 rings are composed of 7 beta
subunits. Proteasomes are distributed throughout eukaryotic cells
at a high concentration and cleave peptides in an
ATP/ubiquitin-dependent process in a non-lysosomal pathway. An
essential function of a modified proteasome, the immunoproteasome,
is the processing of class I MHC peptides. This gene encodes a
member of the proteasome B-type family, also known as the T1B
family, that is a 20S core beta subunit. Proteolytic processing is
required to generate a mature subunit. Expression of this gene is
induced by gamma interferon, and this gene product replaces
catalytic subunit 2 (proteasome beta 7 subunit) in the
immunoproteasome.

None

This antibody is purified through a protein A column, followed by peptide affinity purification.

Supplied in PBS with 0.09% (W/V) sodium azide.

This PSMB10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 214-242 amino acids from the C-terminal region of human PSMB10.

Proteasome subunit beta type-10

Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.